![]() Given this backdrop amid the current COVID-19 pandemic, Gattinoni and colleagues 23 offered the ratio of to evaluate pulmonary gas exchange dysfunction. 22 In the absence of bedside capnography, these substitutes serve an important function.ĭespite the general lack of enthusiasm for measuring V D/V T, bedside capnography is much more widely used to measure end-tidal CO 2 pressure ( ). 20, 21 Another is the ventilatory ratio, which compares arterial partial pressure of CO 2 ( ) and minute ventilation to corresponding “ideal” and “predicted” values as a signifier for V D/V T. ![]() 18, 19 Surrogate measures for estimating V D/V T now are commonly utilized and include versions of the Harris-Benedict or other equations. Unfortunately, it has been our perception that, despite both the clinical value of V D/V T and wide access to indirect calorimetry and volumetric capnography monitors, measuring V D/V T has not been universally embraced by the larger critical care community. 2- 9 Others have demonstrated the value of using V D/V T measurements to detect lung recruitment and de-recruitment, 10- 14 as well as insight into the effects of pharmacologic therapies for ARDS. Since then, numerous studies have confirmed and expanded these findings. The seminal study by Nuckton and colleagues 1 demonstrated that the ratio of physiologic dead space to tidal volume (V D/V T) at ARDS onset was a strong, independent predictor of mortality risk. ![]()
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